The basis of tragedy is man's helplessness against disease, war and death; the basis of comedy is man's helplessness against vanity (the vanity of love, greed, lust, power).
Bio: Samuel Langhorne Clemens, better known by his pen name Mark Twain, was an American author and humorist. He wrote The Adventures of Tom Sawyer and its sequel, Adventures of Huckleberry Finn, the latter often called "The Great American Novel".