The fate of the physiology of the brain is independent of the truth and falsity of my assertions relative to the laws of the organization of the nervous system, in general, and of the brain in particular, just as the knowledge of the functions of a sense is independent of the knowledge of the structure of its apparatus.

Critical Review of Some Anatomical-Physiological Works; With an Explanation of a New Philosophy of the Moral Qualities and Intellectual Faculties (1835)