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As biomedical research continues to provide us with greater understanding and with powerful new tools, the scientific community has, I think, a dual responsibility. One is to push forward the frontiers to make medical advances possible, to understand what cancer is, to develop new ways of treating cancer, to prevent heart disease, and to develop ways of preventing, ultimately, disorders such as Alzheimer's disease and depression. But science also has a second responsibility to society, which is to point out what we need to be concerned about as a society and to bring to bear humane, balanced, and thoughtful ways of dealing with the advances that come from biomedical research. Scientists need to speak to these issues.