It has now become quite clear that the origin of life was not the result of some "happy chance" as was thought till quite recently, but a necessary stage in the evolution of matter. The origin of life is an inalienable part of the general process of the development of the universe and, in particular, the development of the earth.
In principle, one by one, the difficulties of explaining living systems in terms of chemistry and physics disappear. "In principle" are the operative words. In practice the difficulties remain great and seem insurmountable in the foreseeable future. But, from the point of view of the theory of knowledge, there is nevertheless a decisive difference.