To all this, someone is sure to object that life ought to subject itself to reason, to which we will reply that nobody ought to do what he is unable to do, and life cannot subject itself to reason. "Ought, therefore can," some Kantian will retort. To which we shall demur: "Cannot, therefore ought not." And life cannot submit itself to reason, because the end of life is living and not understanding.
The Tragic Sense of Life (1913) - VI : In the Depths of the Abyss