Up till now human life has generally been, as Hobbes described it, "nasty, brutish and short"; the great majority of human beings (if they have not already died young) have been afflicted with misery in one form or another — poverty, disease, ill-health, over-work, cruelty, or oppression. They have attempted to lighten their misery by means of their hopes and their ideals. The trouble has been that the hopes have generally been unjustified, the ideals have generally failed to correspond with reality.
The zestful but scientific exploration of possibilities and of the techniques for realizing them will make our hopes rational, and will set our ideals within the framework of reality, by showing how much of them are indeed realizable.

Transhumanism (1957)