So many people live within unhappy circumstances and yet will not take the initiative to change their situation because they are conditioned to a life of security, conformity, and conservatism, all of which may appear to give one peace of mind, but in reality nothing is more damaging to the adventurous spirit within a man than a secure future. The very basic core of a man's living spirit is his passion for adventure. The joy of life comes from our encounters with new experiences, and hence there is no greater joy than to have an endlessly changing horizon, for each day to have a new and different sun.
First of all, a scientist must be endowed with an imagination, for imagination plays no less important a part in science than it does in art. Imagination is as necessary as is painstaking work on collected material. Without imagination scientific work is just an assortment of facts and conclusions — empty, chaotic, and often barren.
One thing I supplicate your majesty: that you will give orders, under a great penalty, that no bachelors of law should be allowed to come here [the New World]; for not only are they bad themselves, but they also make and contrive a thousand iniquities.
To Ferdinand V of Spain in 1513