Physiologists should not be afraid to act somewhat at random, so as to try - permit me the common expression - fishing in troubled waters. This amounts to saying that, in the midst of the functional disturbances which they produce, they may hope to see some unexpected phenomena emerge which may give direction to their research.

Translated by Henry Copley Greene, An Introduction to the Study of Experimental Medicine (pp. 20-21), Henry Schuman, Inc. 1927