Growing old is natural, growls the old woman. When you've lived long enough for all your ambitions to be in ruins, friendships broken, lovers forgotten or divorced acrimoniously, what's left to go on for? If you feel tired and old in spirit, you might as well be tired and old in body. Anyway, wanting to live forever is immoral. Think of all the resources you're taking up that younger people need! Even uploads face a finite data storage limit after a time. It's a monstrously egotistical statement, to say you intend to live forever.
Chapter 7 (Curator), p. 279 - Accelerando (2005)