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Categories of understanding along with everything else alter as societies change.

William Hardy McNeill
When terms... evolve and change definition with time; and when the social reality which terms are intended to organize and render intelligible is also seen to be in flux, capturing the truth in a net of words becomes a matter of intuition and style more than of any scientific method that can be replicated by others and made to achieve the same result every time someone asks the same question, or undertakes the same operations.

William Hardy McNeill
An irresistible cycle seemed to operate, repeating patterns of the ancient world where civil strife and war brought disaster... I surmised that patterned and predictable changes were in turn rooted in the very nature of civilization—the ineluctable breaker of custom and eroder of moral codes, and itself a product and expression of rapid technological and social change.

William Hardy McNeill
The single most important stimulus to my thought came by chance when I took a course from Robert Redfield entitled "Folk Society." …His approach was to set up antithetical ideal types, expecting to locate any actual human community somewhere along the spectrum of opposites his fieldwork had suggested to him.... But in 1936 his typology had no time dimension. I was so strongly attracted to his scheme that it is scarcely an exaggeration to describe my subsequent intellectual effort as an attempt to explore the missing time dimension of social change as Redfield envisaged it, not in Yucatan but around the whole earth and across recorded time.

William Hardy McNeill
Before the eighteenth century the demographic impact of the profession of medicine remained negligible. Relatively few persons could afford to pay a doctor for his often very expensive services; and for every case in which the doctor's attendance really made a difference between life and death, there were other instances in which even the best available professional services made little difference to the course of the disease, or actually hindered recovery.... Only with the eighteenth century did the situation begin to change; and it was not until after 1850 or so that the practice of medicine and the organization of medical services begin to make large-scale differences in human survival rates and population growth.

William Hardy McNeill