The problem is one in the general physiology of society. The continuance of life and health for any individual depends on maintenance of a moving organic equilibrium within certain definite limits of tolerance. The daily work of the world is done by individuals living their specialized economic and social lives within a moving equilibrium... But specialized progress brought uneven social and economic developments and serious maladjustment. General equilibrium is lost. The limits of tolerance, the margins of safety, are exceeded.
p. 423; as cited in: Wallace Donham at Hmolpedia, 2015 - "The Failure of Business Leadership and the Responsibility of the Universities", 1933