The most terrifying fact about the universe is not that it is hostile but that it is indifferent; but if we can come to terms with this indifference and accept the challenges of life within the boundaries of death — however mutable man may be able to make them — our existence as a species can have genuine meaning and fulfillment. However vast the darkness, we must supply our own light.
Interviewed by Eric Nordern, Playboy (September 1968); later published in Stanley Kubrick: Interviews (2001)