The basis of tragedy is man's helplessness against disease, war and death; the basis of comedy is man's helplessness against vanity (the vanity of love, greed, lust, power).
Bio: Richard E. Dickerson was the first to carry out a single-crystal structure analysis of B-DNA, with what has become known as the "Dickerson dodecamer": C-G-C-G-A-A-T-T-C-G-C-G.