Richard Bergland - Ventricle Quotes

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Despite the evidence that ventricular hormones do not make their way out of the ventricle, the presence of large ventricles in many schizophrenic patients, and the ability of two-dimensional gels to provide a profile of peptides in the ventricle, not a single catheter has been placed into the ventricle of a schizophrenic patient to measure the peptides in the ventricle.... There is no animal model for this disease, the answer can only come from human studies.

Richard Bergland
Somehow the same nurses, physicians, administrators and legal ombudsmen who prevented the study of the ventricular fluid of a patient with senile dimentia, or obesity, or depression, or schizophrenia, because of the risks, will encourage diagnostic tests and therapy for patients with epilepsy that are far more destructive and immutable than the measurement and manipulation of hormones in the ventricle.

Richard Bergland
If the powerful hormone vasopressin, or ADH, is injected into the blood, the body will retain water. If ADH is injected into the ventricle the opposite happens: the body loses water.

Richard Bergland
The ventricles of the human brain... are filled with hormones, and until the hormones swimming in these oceans are dredged out, countless millions of our fellows will remain with brain illnesses that can be neither understood nor treated. Many of their hormone-hungry brains may be fixed as easily as hormone-hungry bodies are fixed with thyroid hormone, insulin, oestrogen and testosterone, but that work cannot begin until cause and effect relationships between brain hormones and brain diseases have been established.

Richard Bergland
The greatest array of brain hormones is found in the ventricle, not in the spinal fluid.

Richard Bergland
Animal experiments have confirmed the necessity of delivering hormones into the ventricle: the powerful hormone endorphin does not change behavior if it is given intravenously; vasopressin will improve memory in animals only if it given into the ventricles; insulin given through the bloodstream does not control apetite but it is the best hormone for such control if given into the brain; and bombesin... only stops stomach ulceration if given into the brain.

Richard Bergland