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Despite the evidence that ventricular hormones do not make their way out of the ventricle, the presence of large ventricles in many schizophrenic patients, and the ability of two-dimensional gels to provide a profile of peptides in the ventricle, not a single catheter has been placed into the ventricle of a schizophrenic patient to measure the peptides in the ventricle.... There is no animal model for this disease, the answer can only come from human studies.
Richard Bergland
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It would be easier... if all animals spoke the same endocrine language, for then correlations made in the laboratory could be quickly moved to the bedside. Unfortunately, such is not the case. The hormone prolactin, for example, has at least seventy-eight different functions in seventy-eight different species
Richard Bergland
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Dandy's experiments were done in the fast lane of science... performed with no control animals, with no record of the number of animals operated on, with no regard for inter-species variability, with no record of the time base, with no histological correlation, with no attempt to quantify the differences and with no involvement with a neutral scientist.
Richard Bergland
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Already in animals, some gland-like cells have been transplanted from the adrenal gland into the brain, where they not only survive but continue their secretions.
Richard Bergland
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The brain has all the characteristics of a gland except one—leaky capillaries—the sturdy brain capillaries are collectively called the 'blood-brain-barrier'. This barrier can easily be demonstrated by injecting a blue dye into an animal; every other organ (except the testacle) turns blue, but the blood-brain barrier keeps the brain as white as snow.
Richard Bergland
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Animal experiments have confirmed the necessity of delivering hormones into the ventricle: the powerful hormone endorphin does not change behavior if it is given intravenously; vasopressin will improve memory in animals only if it given into the ventricles; insulin given through the bloodstream does not control apetite but it is the best hormone for such control if given into the brain; and bombesin... only stops stomach ulceration if given into the brain.
Richard Bergland
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Good authors, too, who once knew better words Now only use four-letter words Writing prose — Anything goes.
Cole Porter
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