Every body and every thing conspire to make me as contented as possible in it; yet I have seen too much of the vanity of human affairs, to expect felicity from the splendid scenes of public life. I am still determined to be cheerful and to be happy, in whatever situation I may be; for I have also learnt, from experience, that the greater part of our happiness or misery depends upon our dispositions, and not upon our circumstances. We carry the seeds of the one or the other about with us, in our minds, wheresoever we go.

Letter to Mercy Warren (1789)