The basis of tragedy is man's helplessness against disease, war and death; the basis of comedy is man's helplessness against vanity (the vanity of love, greed, lust, power).
Bio: Margaret Cavendish, Duchess of Newcastle-upon-Tyne was an English aristocrat, a prolific writer, and a scientist. Born Margaret Lucas, she was the youngest sister of prominent royalists Sir John Lucas and Sir Charles Lucas, who owned the manor of St.