A second conspicuous landmark... is the enunciation of the fundamental law of radioactive disintegration by Rutherford and Soddy in 1903. This law was in no sense a consequence or development of Plank's theories; indeed fourteen years were to elapse before any connection was noticed between the two. The new law asserted that the atoms of radioactive substances broke up spontaneously, and not because of any particular conditions or special happenings. This seemed to involve an even more startling break with classical theory than the new laws of Plank; radioactive break-up appeared to be an effect without a cause, and suggested that the ultimate laws of nature were not even causal.

Physics and Philosophy (1942)