The end of man (as a factual anthropological limit) is announced to thought from the vantage of the end of man (as a determined opening or the infinity of a telos). Man is that which is in relation to his end, in the fundamentally equivocal sense of the word. Since always.

"The Ends of Man," Margins of Philosophy, tr. w/ notes by Alan Bass. The University of Chicago Press. Chicago, 1982. (original French published in Paris, 1972, as Marges de la philosophie). p. 123