The basis of tragedy is man's helplessness against disease, war and death; the basis of comedy is man's helplessness against vanity (the vanity of love, greed, lust, power).
Bio: John Michael Bishop is an American immunologist and microbiologist who shared the 1989 Nobel Prize in Physiology or Medicine with Harold E. Varmus and was co-winner of 1984 Alfred P. Sloan Prize.