If you want to do good research, it's important not to know too much. This almost sounds contradictory but really if you know too much and you get an idea, you will sort of talk yourself out of trying it because you figure it won't work. But if you know just the right amount and you get enthusiastic about your project, you go ahead, you do it and if you're lucky things'll work out.

Interview with Alfred Leitner, "Ivar Giaever's Nobel Prize", 1982