The probability that at ordinary temperatures a macroscopic number of molecules is assembled to give rise to the highly ordered structures and to the coordinated functions characterizing living organisms is vanishingly small. The idea of spontaneous genesis of life in its present form is therefore highly improbable, even on the scale of the billions of years during which prebiotic evolution occurred.

Part 1, p. 23; As cited in: Meyer, Stephen C. "DNA by design: An inference to the best explanation for the origin of biological information." Rhetoric & Public Affairs 1.4 (1998): 551. - Thermodynamics of Evolution (1972)