The horrors of Vivisection have supplanted the solemnity, the thrilling fascination, of the old unetherized operation upon the human sufferer. Their recorded phenomena, stored away by the physiological inquisitor on dusty shelves, are mostly of as little present use to man as the knowledge of a new comet or of a tungstate of zirconium... -contemptibly small compared with the price paid for it in agony and torture.

Medical Education in America (ed. 1871)