E. F. Codd Quote

The adverse impact on development productivity of requiring programmers to navigate along access paths to reach target data [...] was enormous. In addition, it was not possible to make slight changes in the layout in storage without simultaneously having to revise all programs that relied on the previous structure. [...] As a result, far too much manpower was being invested in continual (and avoidable) maintenance of application programs.

Relational Database: A Practical Foundation for Productivity (1982)