Like every other destruction of optimism, whether in a whole civilisation or in a single individual, these must have been unspeakable catastrophes for those who had dared to expect progress. But we should feel more than sympathy for those people. We should take it personally. For if any of those earlier experiments in optimism had succeeded, our species would be exploring the stars by now, and you and I would be immortal.

The Beginning of Infinity: Explanations That Transform the World (ed. Penguin, 2011) - ISBN: 9781101549827