Nature places a simple constraint on those who leave the flock to go their own way: they get eaten. In society it's a bit more complicated. Nonetheless the admonition stands: avoiding the unknown has considerable survival value. Society, nature, and artmaking tend to produce guarded creatures.
Art & Fear: Observations on the Perils (and Rewards) of Artmaking (ed. Image Continuum Press, 2001) - ISBN: 9780961454722