In western civilization, the period ruled by mysticism is known as the 'Dark Ages' and the 'Middle Ages'. I will assume that you know the nature of that period and the state of human existence in those ages. The Renaissance broke the rules of the mystics. "Renaissance" means the "rebirth". Few people today will care to remind you that it was a rebirth of reason - of man's mind.
Philosophy: Who Needs It (ed. Penguin, 1984) - ISBN: 9781101137703