Arthur Conan Doyle Quote

What is the meaning of it, Watson? said Holmes solemnly as he laid down the paper. "What object is served by this circle of misery and violence and fear? It must tend to some end, or else our universe is ruled by chance, which is unthinkable. But what end? There is the great standing perennial problem to which human reason is as far from an answer as ever.

The Complete Sherlock Holmes (ed. 1960)