It is a remarkable fact in the history of science, that the more extended human knowledge has become, the more limited human power, in that respect, has constantly appeared. This globe, of which man imagines the haughty possessor, becomes, in the eyes of astronomer, merely a grain of dust floating in immensity of space: an earthquake, a tempest, an inundation, may destroy in an instant an entire people, or ruin the labours of twenty ages.... But if each step in the career of science thus gradually diminishes his importance, his pride has a compensation in the greater idea of his intellectual power, by which he has been enabled to perceive those laws which seem to be, by their nature, placed for ever beyond his grasp.
Introductory - A Treatise on Man and the Development of His Faculties (1842)